Invitrogen™ DENND1C Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA546140

Product Code. 15567072

Description

Peptide sequence: PSSLEDPRAR PPKALLAERA HLQPREEPGA LNSPATPTSN CQKSQPSSRP Sequence homology: Human: 100%.

Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.

Specifications

• Antigen: DENND1C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DENND1C
• Gene Alias: Connecdenn 3; DENN domain containing 1C; DENN domain-containing protein 1C; DENN/MADD domain containing 1C; DENND1C; FAM31C; family with sequence similarity 31, member C; Protein FAM31C
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79958
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8IV53
• Gene Symbols: DENND1C
• Immunogen: Synthetic peptide directed towards the C-terminal of human DENND1C (aa 741-790).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG