(+)-Dehydroisoandrosterone, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity	Packaging
10103400	Thermo Scientific Acros 154980025	2.5 g	Glass bottle
10488310	Thermo Scientific Acros 154980100	10 g	Glass bottle
10399323	Thermo Scientific Acros 154980500	50 g	Glass bottle

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• (+)-Dehydroisoandrosterone is an endogenous steroid hormone precursor that acts as an intermediate in the conversion of cholesterol to androgens and estrogens

Applications

• It is an endogenous and naturally occurring steroid hormone produced largely by the adrenal glands, but also by the testes and ovaries

• It has been described that (+)-Dehydroisoandrosterone could have a role in the immune and stress response

• (+)-Dehydroisoandrosterone can be converted to testosterone, androstenedione, estradiol, and estrone

• (+)-Dehydroisoandrosterone is derived from cholesterol through the action of two cytochrome P450 enzymes

• It can induce both direct and indirect in vivo biological effects, by modulating GABA- α receptor and N-Methyl-D-aspartic acid (NMDA) receptor complexes.

• It can also increase pancreatic β cell insulin secretion and anti-glucocorticoid activity

• It is useful to detect excess adrenal activity since it is produced nearly exclusively by the adrenal glands

Chemical Identifiers

• CAS: 53-43-0
• Molecular Weight (g/mol): 288.42
• InChI Key: FMGSKLZLMKYGDP-USOAJAOKSA-N
• PubChem CID: 5881
• IUPAC Name: (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one

• Molecular Formula: C₁₉H₂₈O₂
• MDL Number: MFCD00003613
• Synonym: dehydroepiandrosterone, dhea, prasterone, dehydroisoandrosterone, androstenolone, trans-dehydroandrosterone, 3beta-hydroxyandrost-5-en-17-one, diandron, diandrone, psicosterone
• ChEBI: CHEBI:28689
• SMILES: CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C

Specifications

• CAS: 53-43-0
• CAS Max %: 100.0
• Color: White
• Infrared Spectrum: Authentic
• Molecular Formula: C₁₉H₂₈O₂
• Beilstein: 08, IV, 994
• Specific Rotation: + 12.00
• Solubility Information: Solubility in water: practically insoluble. Other solubilities: soluble in benzene,alcohol and diethyl ether,sparingly soluble in chloroform and petrol. ether
• SMILES: CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C
• Molecular Weight (g/mol): 288.42
• ChEBI: CHEBI:28689
• Percent Purity: 99%
• Chemical Name or Material: (+)-Dehydroisoandrosterone

• CAS Min %: 98.5
• Melting Point: 146.0°C to 151.0°C
• Loss on Drying: 0.5% max. (105°C, 3 hrs)
• Assay Percent Range: 98.5% min. (HPLC)
• MDL Number: MFCD00003613
• Merck Index: 15, 2875
• Synonym: dehydroepiandrosterone, dhea, prasterone, dehydroisoandrosterone, androstenolone, trans-dehydroandrosterone, 3beta-hydroxyandrost-5-en-17-one, diandron, diandrone, psicosterone
• InChI Key: FMGSKLZLMKYGDP-USOAJAOKSA-N
• IUPAC Name: (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
• PubChem CID: 5881
• Formula Weight: 288.42
• Physical Form: Fine Crystalline Powder

Safety and Handling

missing translation for 'einecsNumber' : 200-175-5

RUO – Research Use Only