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Deguelin, MedChemExpress

Product Code. 16485678
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Product Code. 16485678 Supplier Medchem Express Supplier No. HY13425
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Estimated Shipment: 20-11-2026
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Description

MedChemExpress Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.

Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.

Specifications

Chemical Name or Material Deguelin
CAS 522-17-8
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C23H22O6
Quantity 10 mg
Synonym (-)-Deguelin (-)-cis-Deguelin
Solubility Information DMSO : 100 mg/mL (253.54 mM; Need ultrasonic)
SMILES O=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14
Molecular Weight (g/mol) 394.42
Formula Weight 394.42
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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