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Defactinib hydrochloride, MedChemExpress

Product Code. 16477787
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Product Code. 16477787

Brand: Medchem Express HY12289A

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Description

MedChemExpress Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.

Defactinib hydrochloride (VS-6063 hydrochloride

Specifications

Chemical Name or Material Defactinib hydrochloride
CAS 1073160-26-5
Color Off-White
Purity Grade Notes Research
Molecular Formula C20H22ClF3N8O3S
Quantity 5 mg
Synonym VS-6063 hydrochloride PF 04554878 hydrochloride
Solubility Information DMSO : 30 mg/mL (54.85 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(NC)C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=NC=CN=C3N(C)S(=O)(C)=O)=N2)C=C1.[H]Cl
Molecular Weight (g/mol) 546.95
Formula Weight 546.95
Percent Purity 98.03%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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