Invitrogen™ Defensin 5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA582540

Product Code. 16329504

Description

Immunogen sequence: ESLQERADEA TTQKQSGEDN QDLAISFAGN GLSALRTSGS QARATCYCRT GRCATRESLS GVCEISGRLY RLCCR Highest antigen sequence indentity to the following orthologs: Rat - 49%, Mouse - 39%.

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

Specifications

• Antigen: Defensin 5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEFA5
• Gene Alias: DEF5; DEFA5; defensin 5; defensin alpha 5; Defensin, alpha 5; defensin, alpha 5, Paneth cell-specific; defensin, alpha 5, preproprotein; defensin-5; HD5; HD-5; HD5(20-94); HD5(23-94); HD5(29-94); HD5(56-94); HD5(63-94); MGC129728
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1670
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q01523
• Gene Symbols: DEFA5
• Immunogen: Recombinant protein fragment of Human DEFA5 (Product #RP-89636)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG