Invitrogen™ DEFA4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA562362

Product Code. 15700162

Description

Immunogen sequence: SSALQVSGST RGMVCSCRLV FCRRTELRVG NCLIGGVSFT YCCTRVD Highest antigen sequence identity to the following orthologs: Mouse - 32%, Rat - 36%.

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.

Specifications

• Antigen: DEFA4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEFA4
• Gene Alias: Alpha-defensin 4; corticostatin; Crp4; DEF4; Defa28; Defa4; Defcr4; defensin alpha 4; Defensin, alpha 4; defensin, alpha 4, corticostatin; defensin, alpha 4, preproprotein; defensin, alpha, 4; Defensin-related cryptdin-4; HNP-4; HP4; HP-4; Neutrophil defensin 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1669
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P12838
• Gene Symbols: DEFA4
• Immunogen: Recombinant protein corresponding to Human Defensin. Recombinant protein control fragment (Product #RP-101423).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG