Invitrogen™ DEDD Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583152

Product Code. 16310115

Description

Immunogen sequence: RGRATLGSQR KRRKSVTPDP KEKQTCDIRL RVRAEYCQHE TALQGNVFSN KQDPLERQFE RFNQANTILK SRDLGSIICD IKFSELTYLD AFWRDYINGS LLEALKGVFI TDSLKQAVGH EAIKLLVNV Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.

DEDD encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: DEDD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEDD
• Gene Alias: CASP8IP1; death effector domain containing; death effector domain-containing; death effector domain-containing protein; Death effector domain-containing testicular molecule; DEDD; DEDD1; Dedpro1; DEFT; FLDED1; FLDED-1; KE05; tumor necrosis factor (ligand) superfamily, member 19
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9191
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75618
• Gene Symbols: DEDD
• Immunogen: Recombinant protein corresponding to Human DEDD. Recombinant protein control fragment (Product #RP-104613).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG