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Decitabine, MedChemExpress

Product Code. 16487976
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Product Code. 16487976

Brand: Medchem Express HYA0004

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Description

MedChemExpress Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.

Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity.

Specifications

Chemical Name or Material Decitabine
CAS 2353-33-5
Color White
Purity Grade Notes Research
Molecular Formula C8H12N4O4
Quantity 100 mg
Synonym 5-Aza-2'-deoxycytidine 5-AZA-CdR NSC 127716
Solubility Information DMSO : ≥ 50 mg/mL (219.10 mM) ∣H2O : 20 mg/mL (87.64 mM; Need ultrasonic)
SMILES O=C1N=C(N)N=CN1[C@H](O[C@@H]2CO)C[C@@H]2O
Molecular Weight (g/mol) 228.21
Formula Weight 228.21
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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