Invitrogen™ DDX4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530749

Product Code. 14817501

Description

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Mouse (92%), Rat (88%), Pig (98%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: DDX4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DDX4
• Gene Alias: ATP-dependent RNA helicase DDX4; AV206478; Cvh; Ddx4; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; DEAD box polypeptide 4; DEAD box protein 4; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4; DEAD-box helicase 4; MGC111074; Mvh; mvh / m'vasa; probable ATP-dependent RNA helicase DDX4; putative ATP-dependent RNA helicase DDX4; RVLG; VASA; Vasa homolog; vasa-like gene protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13206, 54514
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Free Floating), Western Blot, Immunocytochemistry
• Concentration: 1.36 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q61496, Q9NQI0
• Gene Symbols: DDX4
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human DDX4. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Fish, Human, Mouse
• Product Type: Antibody
• Isotype: IgG