DDX3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16847973	Proteintech 11115-1-AP-20UL	20 μL
16837973	Proteintech 11115-1-AP-150UL	150 μL

Description

This antibody can bind both DDX3X and DDX3Y for the close sequences.

The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: DDX3
• Applications: Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Human, Rat
• Gene Accession No.: O00571, Q62167
• Gene ID (Entrez): 13205, 1654, 317335
• Immunogen: DDX3 Fusion Protein Ag1614
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DDX3X

• Concentration: 0.24 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: DBX, DDX14, DDX3, DDX3X, DEAD box, X isoform, Helicase like protein 2, HLP2
• Gene Symbols: Ddx3x
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody