Invitrogen™ DDOST Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA561347

Product Code. 15779161

Description

Immunogen sequence: NYELAVALSR WVFKEEGVLR VGPVSHHRVG ETAPPNAYTV TDLVEYSIVI QQLSNGKWVP FDGDDIQLEF VRIDPFVRTF LKKKGGKYSV QFKLPDVYGV FQFKVDYNRL GYTHLYSSTQ VSVRPLQHTQ Y Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.

This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation end products (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.

Specifications

• Antigen: DDOST
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DDOST
• Gene Alias: advanced glycation endproduct receptor 1; advanced glycation end-product receptor 1; AGER1; AGE-R1; CDG1R; Ddost; DDOST 48 kDa subunit; dolichyl-diphosphooligosaccharide protein glycosyltransferase; dolichyl-diphosphooligosaccharide-protein glycosyltransferase; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic); dolichyl-di-phosphooligosaccharide-protein glycotransferase; dolichyl-diphosphooligosaccharide-protein glycotransferase; KIAA0115; MGC2191; OK/SW-cl.45; OKSWcl45; oligosaccharyl transferase 48 kDa subunit; oligosaccharyltransferase 48 kDa subunit; oligosaccharyltransferase OST48; oligosaccharyltransferase subunit 48; OST; OST48; WBP1; wu:fa11d01; zgc:66068; zgc:66068 protein; zgc:77478
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1650
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P39656
• Gene Symbols: DDOST
• Immunogen: Recombinant protein corresponding to Human DDOST. Recombinant protein control fragment (Product #RP-103000).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG