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DCPIB, MedChemExpress

Product Code. 16486557
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100 mg
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Product Code. 16486557

Brand: Medchem Express HY103371

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Description

MedChemExpress DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC).

DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK, and inhibits TRESK, TASK1 and TASK3 (IC50s: 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM. DCPIB is a useful tool for investigating structure-function studies of K2P channels.

Specifications

Chemical Name or Material DCPIB
CAS 82749-70-0
Color White
Purity Grade Notes Research
Molecular Formula C22H28Cl2O4
Quantity 5 mg
Solubility Information DMSO : 100 mg/mL (233.99 mM; Need ultrasonic)
SMILES O=C(O)CCCOC1=CC2=C(C(C(C3CCCC3)(CCCC)C2)=O)C(Cl)=C1Cl
Molecular Weight (g/mol) 427.36
Formula Weight 427.36
Percent Purity 99.7%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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