Invitrogen™ DCP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA531091

Product Code. 13435607

Description

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (86%), Xenopus laevis (86%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The removal, or decapping, of eukaryotic mRNA is an important step in the degradation of mRNA. Decapping protein 2 (DCP2) is the major mRNA decapping enzyme in cells. It is a member of the Nudix hydrolases superfamily of proteins that predominantly catalyze the hydrolysis of small nucleoside diphosphate substrates linked to another moiety. DCP2 is widely expressed in multiple tissues at varying levels, with highest expression seen in testis and brain.

Specifications

• Antigen: DCP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DCP2
• Gene Alias: 2410015D23Rik; 5730537H01Rik; AL118268; DCP2; DCP2 decapping enzyme homolog; DCP2 decapping enzyme homolog (S. cerevisiae); decapping mRNA 2; Decapping protein 2; DFLJ33245; hDpc; m7GpppN-mRNA hydrolase; mRNA decapping enzyme 2; mRNA-decapping enzyme 2; Nucleoside diphosphate-linked moiety X motif 20; nudix (nucleoside diphosphate linked moiety X)-type motif 20; nudix (nucleoside diphosphate linked moiety X)-type motif 20 (NUDT20); Nudix motif 20; nudix-type motif 20; NUDT20; RGD1562909
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 167227, 70640
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.64 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8IU60, Q9CYC6
• Gene Symbols: DCP2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human DCP2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG