Invitrogen™ DCLK1 Monoclonal Antibody (C9), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA550942

Product Code. 17949792

Description

DCAMKL1 (DCLK1) serine/threonine kinase or DCLK1 or doublecortin-like kinase 1 contains two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (which shows substantial homology to Ca2+/calmodulin-dependent protein kinase), and a serine/proline-rich domain in between the doublecortin and the protein kinase domains (which mediates multiple protein-protein interactions). DCAMKL1 is a microtubule-associated kinase that can undergo autophosphorylation. DCAMKL1 has microtubule-polymerizing activity that is independent of its protein kinase activity. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis.

Specifications

• Antigen: DCLK1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Accession No.: O08875, O15075
• Gene Symbols: DCLK1
• Immunogen: Recombinant Human DCLK1 protein, Tyr390-Val647 (Accession #O15075).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig, Rat
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Clone: C9
• Conjugate: Unconjugated
• Gene: DCLK1
• Gene Alias: 1700113D08Rik; 2810480F11Rik; AI836758; Ania4; Calcium/calmodulin-dependent protein kinase type I-like CPG16; CL1; CLICK1; Click-I; CLICK-I beta; Cpg16; Dcamkl1; DCDC3A; Dcl; Dclk; Dclk1; double cortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin domain-containing protein 3A; doublecortin like kinase 1; doublecortin-like and CAM kinase-like 1; Doublecortin-like kinase 1; KIAA0369; mKIAA0369; RP11-113P14.1; Serine/threonine-protein kinase DCLK1
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 100623824, 83825, 9201
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid