Invitrogen™ DCK Monoclonal Antibody (GT7710)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA527741

Product Code. 16312254

Description

Positive Control: HeLa, HepG2, 293T, A549, H1299, HCT116 Predicted Reactivity: Rhesus Monkey (96%), Bovine (95%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

Specifications

• Antigen: DCK
• Classification: Monoclonal
• Concentration: 1.33 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P27707, P43346, P48769
• Gene Symbols: DCK
• Immunogen: Recombinant protein encompassing a sequence within the center region of human DCK. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: GT7710
• Conjugate: Unconjugated
• Gene: DCK
• Gene Alias: DCK; Deoxycytidine kinase; deoxynucleoside kinase
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 13178, 1633, 79127
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid