Invitrogen™ DCAMKL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5106515

Product Code. 16632955

Description

Immunogen sequence for PA5-106515 is ELEHFEERDKRPRP. Antibody detects endogenous levels of total DCLK2.

DCAMKL2 is a serine/threonine kinase involved in signal transduction and cellular communication, and is the human homolog of a rat protein kinase expressed in cerebrocortical lamination that binds microtubules. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

Specifications

• Antigen: DCAMKL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DCLK2
• Gene Alias: 6330415M09Rik; AU044875; CaMK-like CREB regulatory kinase 2; CL2; CLICK2; Click-II; CLIK2; DCAMKL2; DCDC3; DCDC3B; DCK2; DCLK2; doublecortin and CaM kinase-like 2; doublecortin domain-containing protein 3B; doublecortin kinase 2; doublecortin like kinase 2; doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; RGD1308384; Serine/threonine-protein kinase DCLK2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 166614, 70762
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6PGN3, Q8N568
• Gene Symbols: DCLK2
• Immunogen: A synthesized peptide derived from human DCLK2(Accession Q8N568), corresponding to amino acid residues M1-G38.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG