Invitrogen™ Human DCAMKL1 (DCLK1), GST Tag Recombinant Protein

Product Code. 17138775

Brand: Invitrogen™ A33355

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This DCAMKL1 (DCLK1) recombinant human protein (full length) was expressed in insect cells. DCAMKL1 (DCLK1) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Full Length, Recombinant, Active The gene accession number for DCAMKL1 (DCLK1) is NP_004725.1.

DCAMKL1 (DCLK1) serine/threonine kinase or DCLK1 or doublecortin-like kinase 1 contains two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (which shows substantial homology to Ca2+/calmodulin-dependent protein kinase), and a serine/proline-rich domain in between the doublecortin and the protein kinase domains (which mediates multiple protein-protein interactions). DCAMKL1 is a microtubule-associated kinase that can undergo autophosphorylation. DCAMKL1 has microtubule-polymerizing activity that is independent of its protein kinase activity. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis.

Specifications

• Accession Number: O15075
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris HCl with 0.1mM EDTA, 25% glycerol, 0.1mM PMSF, 150mM NaCl, 0.25mM DTT, 10mM glutathione and no preservative; pH 7.5
• Gene ID (Entrez): 9201
• Molecular Weight (g/mol): 107.4 kDa
• Name: Human DCAMKL1 (DCLK1), GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 1 mg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 1700113D08Rik; 2810480F11Rik; AI836758; Ania4; Calcium/calmodulin-dependent protein kinase type I-like CPG16; CL1; CLICK1; Click-I; CLICK-I beta; Cpg16; Dcamkl1; DCDC3A; Dcl; Dclk; Dclk1; double cortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin domain-containing protein 3A; doublecortin like kinase 1; doublecortin-like and CAM kinase-like 1; Doublecortin-like kinase 1; KIAA0369; mKIAA0369; RP11-113P14.1; Serine/threonine-protein kinase DCLK1
• Common Name: DCLK1
• Gene Symbol: DCLK1
• KinaseFamily: DCAMKL Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Shipping Condition: Dry Ice
• Expression System: Insect cells
• Protein Form: Full Length, Recombinant, Active
• Form: Liquid