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  6. Invitrogen™ DAZAP1 Recombinant Rabbit Monoclonal Antibody (K01_3L31)

Invitrogen™ DAZAP1 Recombinant Rabbit Monoclonal Antibody (K01_3L31)

Product Code. 30827412
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30827412 50 μL
30826298 100 μL
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Product Code. 30827412 Supplier Invitrogen™ Supplier No. MA565849

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Description

Rabbit Recombinant Monoclonal Antibody

DAZAP1 Recombinant Monoclonal Antibody for Western Blot

The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors. The receptor is more than 90 kDa and has three major functional domains: the N-terminal domain, DNA-binding domain, and the androgen-binding domain. The androgen receptor is a ligand-activated transcription factor that binds active testosterone (T) and dihydrotestosterone (DHT). Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis.AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain.Androgen Receptor is a phosphoprotein, and also regulates mitogen-activated protein kinase (MAP kinase). The inhibition of the MEK1/2 pathway correlates directly with a change in phosphorylation state of the androgen receptor. Abnormalities in the AR signaling pathway have been linked to a number of diseases, including prostate cancer, Kennedy's disease, and male infertility. Mutations in this gene are associated with complete androgen insensitivity (CAIS).
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAZAP1
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_3L31
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene DAZAP1
Gene Accession No. Q96EP5, Q9JII5
Gene Alias 2410042M16Rik; DAZ associated protein 1; DAZAP1; DAZ-associated protein 1; Deleted in azoospermia-associated protein 1; LOC561459 protein; LOW QUALITY PROTEIN: DAZ-associated protein 1; MGC19907; mPrrp; testicular tissue protein Li 50
Gene Symbols DAZAP1
Host Species Rabbit
Immunogen Recombinant protein of human DAZAP1.
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26528, 362836, 70248
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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