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Eurofins DiscoverX DAPK1 Protein, Active
Description
Death-associated protein kinase 1 (DAPK1) is a calcium/calmodulin-dependent kinase that phosphorylates serine/threonine residues on proteins. DAPK1 modulates cell death induced by IFN-γ, TNF-α, Fas, and detachment from the extracellular matrix. DAPK1 has been also implicated in TGF-β-induced apoptosis in several cultured cell lines in which Smad proteins mediate transcriptional activation of DAPK1.
GenBank NM_004938
Specifications
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molecular Weight (g/mol) | 60.9 kDa |
| Quantity | 250 μg |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal GST |
| Expression System | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Truncated |
| Purity or Quality Grade | ≥77% |
| Protein | DAPK1, active |
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