missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. Daphnetin, MedChemExpress

Daphnetin, MedChemExpress

Product Code. 16428938
Encompass_Preferred
Click to view available options
Quantity:
10 mg
50 mg
100 mg
Unit Size:
100mg
10mg
50mg
This item is not returnable. View return policy

Product Code. 16428938

Brand: Medchem Express HYN0281

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively.

Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1ß, ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research.

Specifications

Chemical Name or Material Daphnetin
Physical Form Solid
CAS 486-35-1
Color Light Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C9H6O4
For Use With (Application) COVID-19-immunoregulation
Synonym 7,8-Dihydroxycoumarin
Solubility Information DMSO : 50 mg/mL (280.68 mM; Need ultrasonic) ∣H2O : 1 mg/mL (5.61 mM; Need ultrasonic)
SMILES O=C1C=CC2=CC=C(O)C(O)=C2O1
Molecular Weight (g/mol) 178.14
Formula Weight 178.14
Percent Purity 99.21%
Grade Research
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.