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Description
Immunogen sequence: QDTVELREHH WVPRKAFLDN GPKTINQIRQ DAVKDLGVFI PAPMAQGMRS DFFLEGPFMP PRMKMDRDPL GGLADMFGQM PGSGIGTGPG VIQDRFSPTM GRHRSNQLFN GHGGHIMPPT QSQFGEMGGK FMKSQGLSQL YH Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
CDK5RAP2 is a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein is localized to the centrosome and Golgi complex and interacts with CDK5R1 and pericentrin (PCNT). CDK5RAP2 plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Specifications
Specifications
| Antigen | DAP5 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Eif4g2 |
| Gene Accession No. | P78344, Q62448 |
| Gene Alias | AA589388; AAG1; aging-associated protein 1; DAP5; DAP-5; Death-associated protein 5; E130105L11Rik; eIF4G 2; eIF-4G 2; EIF4G2; eif4g2.L; eif4g2.S; eIF-4-gamma 2; Eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4 gamma, 2; eukaryotic translation initiation factor 4 gamma, 2 L homeolog; eukaryotic translation initiation factor 4 gamma, 2 S homeolog; eukaryotic translation initiation factor 4 gamma, 2 S homeolog; eukaryotic translation initiation factor 4, gamma 2; eukaryotic translation initiation factor 4G-like 1; FLJ41344; NAT1; Natm1; Novel APOBEC-1 target 1; OK/SW-cl.75; p97; translation repressor NAT1; XELAEV_18024574mg |
| Gene Symbols | Eif4g2 |
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