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Invitrogen™ DAP3 Polyclonal Antibody
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Product Code. 13464177
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Quantity:
100 μL
Unit Size:
100µL
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13464177 100 μL 100µL
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Product Code. 13464177 Supplier Invitrogen™ Supplier No. PA529851

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (85%), Rat (87%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Splice variants that differ in the 5' UTR have been found for this gene; both variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAP3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene DAP3
Gene Accession No. P51398
Gene Alias 28S ribosomal protein S29, mitochondrial; 4921514D13Rik; bMRP-10; DAP3; DAP-3; death associated protein 3; death-associated protein 3; DKFZp686G12159; Ionizing radiation resistance conferring protein; MGC126058; MGC126059; mitochondrial 28S ribosomal protein S29; Mitochondrial small ribosomal subunit protein mS29; MRPS29; MRP-S29; S29mt
Gene Symbols DAP3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human DAP3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7818
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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