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Invitrogen™ DAB2 Recombinant Rabbit Monoclonal Antibody (K01_2M07)
Description
DAB2 Recombinant Monoclonal Antibody for IHC (P), Western Blot
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta).
Specifications
Specifications
| Antigen | DAB2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_2M07 |
| Concentration | 0.7 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4 |
| Gene | DAB2 |
| Gene Accession No. | P98082 |
| Gene Alias | 5730435J12Rik; AA960054; Adaptor molecule disabled-2; AI957090; C9; D15Wsu122e; D630005B22Rik; Dab, mitogen-responsive phosphoprotein, homolog 2; Dab2; DAB2, clathrin adaptor protein; differentially expressed in ovarian carcinoma 2; Differentially-expressed protein 2; disabled 2, mitogen-responsive phosphoprotein; disabled homolog 2; disabled homolog 2 mitogen-responsive phosphoprotein; disabled homolog 2, mitogen-responsive phosphoprotein; Doc2; Doc-2; DOC-2 p82 isoform; FLJ26626; Mitogen-responsive phosphoprotein; p96 |
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