Invitrogen™ DAB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102914

Product Code. 16689364

Description

Antibody detects endogenous levels of total DAB2.

DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta).

Specifications

• Antigen: DAB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DAB2
• Gene Alias: 5730435J12Rik; AA960054; Adaptor molecule disabled-2; AI957090; C9; D15Wsu122e; D630005B22Rik; Dab, mitogen-responsive phosphoprotein, homolog 2; Dab2; DAB2, clathrin adaptor protein; differentially expressed in ovarian carcinoma 2; Differentially-expressed protein 2; disabled 2, mitogen-responsive phosphoprotein; disabled homolog 2; disabled homolog 2 mitogen-responsive phosphoprotein; disabled homolog 2, mitogen-responsive phosphoprotein; Doc2; Doc-2; DOC-2 p82 isoform; FLJ26626; Mitogen-responsive phosphoprotein; p96
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13132, 1601
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P98078, P98082
• Gene Symbols: DAB2
• Immunogen: A synthesized peptide derived from human DAB2(Accession P98082), corresponding to amino acid residues F738-A770.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG