Invitrogen™ D4-GDI Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA527873

Product Code. 13431837

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji , mouse fibroblast. Predicted reactivity: Mouse (90%), Rat (89%), Xenopus laevis (81%), Pig (94%), Chicken (92%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.

Specifications

• Antigen: D4-GDI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARHGDIB
• Gene Alias: ARHGDIB; D4; d4 gdi; GDI LYGDI; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP dissociation inhibitor beta; rho GDP-dissociation inhibitor 2; Rho, GDP dissociation inhibitor (GDI) beta; rho-GDI beta; RhoGDI2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11857, 397
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P52566, Q61599
• Gene Symbols: ARHGDIB
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Rho GDI2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG