Cytokeratin, LMW Antibody (AE-1), PE, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-33178PE

Product Code. 18163235

Description

Cytokeratin, LMW Monoclonal specifically detects Cytokeratin, LMW in Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Rabbit, Reptile samples. It is validated for Flow Cytometry.

Specifications

• Antigen: Cytokeratin, LMW
• Classification: Monoclonal
• Conjugate: PE
• Gene Alias: Cytokeratin LMW, cytokeratin-1B, keratin 77, keratin, type II cytoskeletal 1b, KRT77, type-II keratin Kb39
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 374454
• Target Species: Human, Mouse, Rat, Bovine, Canine, Chicken, Other, Primate, Rabbit
• Form: Purified

• Applications: Flow Cytometry
• Clone: AE-1
• Dilution: Flow Cytometry
• Gene Symbols: KRT77
• Immunogen: Human epidermal keratin (Uniprot: Q7Z794)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: This monoclonal antibody recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI, 48, 46, 45, and 40kDa. monoclonal antibody AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

For Research Use Only