Cytokeratin 8/18 Antibody (C-51) - IHC-Prediluted, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-48179

Product Code. 18195219

Description

Cytokeratin 8/18 Monoclonal specifically detects Cytokeratin 8/18 in Human, Rat, Porcine, Bovine, Ferret (Negative), Monkey, Sheep, Chicken (Negative), Donkey (Negative), Mouse (Negative), Rabbit (Negative), Xenopus (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Cytokeratin 8/18
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: KRT8
• Immunogen: Cytoskeleton preparation from HeLa cells
• Quantity: 7 mL
• Research Discipline: Cancer, Cytoskeleton Markers
• Gene ID (Entrez): 3856
• Target Species: Human, Rat, Pig, Ferret (Negative), Primate, Monkey, Sheep, Chicken (Negative), Donkey (Negative), Mouse (Negative), Rabbit (Negative), Xenopus (Negative)
• Form: Purified

• Applications: Immunohistochemistry (Paraffin)
• Clone: C-51
• Dilution: Immunohistochemistry-Paraffin
• Gene Alias: CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ