Cytokeratin 19 Mouse anti-Human, eFluor 570, Clone: BA17, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 41-9898-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15381080

Quantity Price
1 £ 67.82 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Isotype IgG1
Primary or Secondary Primary
Host Species Mouse
Applications Immunocytochemistry
Applications Immunohistochemistry
Conjugate eFluor 570
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen Cytokeratin 19
Concentration 0.2mg/mL
Gene Alias CK19, Keratin 19
Regulatory Status RUO
Species Reactivity Human
Clone BA17
Quantity 25μg

This BA17 monoclonal antibody reacts with human cytokeratin 19 (CK19), a 44kDa type I (acidic) intermediate filament protein that lacks the non-alpha-helical tail domain present in other keratins. Cytokeratins form the intracellular cytoskeletal network that maintains the integrity and stability of cells and tissues. Cytokeratin 19 is expressed in a wide variety of simple and stratified epithelial tissue. Moreover, cytokeratin 19 expression can be induced by vitamin A, SV40 transformation, and cancer. A soluble form of cytokeratin 19 generated by caspase 3 cleavage has also been found to be secreted by cancer cells, thus possibly indicating tumor metastasis. Cytokeratin 19 often exists as a heterodimer with cytokeratin 7, a type II keratin.