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Description
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e.., skin) and non-keratinizing cells (i.e.. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.
Specifications
Specifications
| Antigen | Cytokeratin 10 |
| Applications | Immunohistochemistry (Paraffin), Flow Cytometry |
| Classification | Polyclonal |
| Concentration | 0.24 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | KRT10 |
| Gene Accession No. | P02535, P13645, Q6IFW6 |
| Gene Alias | CK 10, CK10, Cytokeratin 10, K10, keratin 10, KPP, KRT10 |
| Gene Symbols | Krt10 |
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Product Title
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