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Invitrogen™ Cystatin C Monoclonal Antibody (5H2)
Description
MA5-15841 targets CST3 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15841 immunogen is purified recombinant fragment of human CST3 expressed in E. Coli. . MA5-15841 detects CST3 which has a predicted molecular weight of approximately 42kDa.
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
Specifications
Specifications
| Antigen | Cystatin C |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 5H2 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | ascites with 0.03% sodium azide |
| Gene | Cst3 |
| Gene Accession No. | P01034 |
| Gene Alias | AD8; ARMD11; bA218C14.4 (cystatin C); CST3; CYSC; cystatin; cystatin 3; cystatin C; cystatin C (amyloid angiopathy and cerebral hemorrhage); Cystatin C (cysteine proteinase inhibitor); Cystatin3; cystatin-3; CystatinC; Cystatin-C; epididymis secretory protein Li 2; fb51d07; Gamma-trace; HEL-S-2; MGC117328; neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; Post-gamma-globulin; RP23-250M11.9; wu:fb24g06; wu:fb51d07; wu:fc55f03; zgc:136227 |
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