Invitrogen™ CYSLTR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102071

Product Code. 16658544

Description

Antibody detects endogenous levels of total CLTR1.

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.

Specifications

• Antigen: CYSLTR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYSLTR1
• Gene Alias: BB147369; CysLT 1; CysLT(1); Cyslt1; CysLT1 receptor; Cys-LT1 receptor; Cyslt1r; CYSLTR; Cysltr1; cysteinyl leukotriene 1 receptor short isoform; cysteinyl leukotriene D4 receptor; Cysteinyl leukotriene receptor 1; G-protein coupled receptor HG55; HG55; HMTMF81; LTD4 receptor; LTD4R; MGC46139
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10800
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9Y271
• Gene Symbols: CYSLTR1
• Immunogen: A synthesized peptide derived from human CYSLTR1(Accession Q9Y271), corresponding to amino acid residues K139-L189.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey
• Product Type: Antibody
• Isotype: IgG