Invitrogen™ CYP3A7 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
17960453	Invitrogen™ PA5145345	200 μL
17990843	Invitrogen™ PA5145346	20 μL

Description

This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.

Specifications

• Antigen: CYP3A7
• Applications: Western Blot, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P24462
• Gene ID (Entrez): 1551
• Immunogen: Recombinant Human CYP3A7 protein, Pro344-Asp497 (Accession #P24462).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

• Concentration: 0.5 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Alias: aryl hydrocarbon hydroxylase; CP37; CYP3A7; CYPIIIA7; Cytochrome P450 3A7; cytochrome P450 family 3 subfamily A member 7; cytochrome P450, family 3, subfamily A, polypeptide 7; cytochrome P450, subfamily IIIA, polypeptide 7; cytochrome P450-HFLA; flavoprotein-linked monooxygenase; microsomal monooxygenase; P-450(HFL33); P-450111A7; P450-HFLA; P450HLp2; xenobiotic monooxygenase
• Gene Symbols: CYP3A7
• Isotype: IgG
• Purification Method: Antigen affinity chromatography, Protein A
• Gene: CYP3A7