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Invitrogen™ CYP3A4/CYP3A5 Monoclonal Antibody (F24 P2 B10)
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Product Code. 11595742
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
11595742 100 μL 100µL
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Product Code. 11595742 Supplier Invitrogen™ Supplier No. MA3032

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Description

Mouse Monoclonal Antibody

MA3-032 detects Cytochrome P450 3A4/3A5 from human cell line HepG2, and from bovine liver and pancreas samples. MA3-032 has been successfully used in Western blot applications. By Western blot, this antibody detects a ~54 kDa band representing Cytochrome P450 3A4/3A5. The MA3-032 immunogen is a synthetic peptide corresponding to residues E S R D G T V S G A, conjugated to ovalbumin.

CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP3A4/CYP3A5
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone F24 P2 B10
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.05% sodium azide
Gene CYP3A4
Gene Accession No. P08684, P20815
Gene Alias 1,8-cineole 2-exo-monooxygenase; albendazole monooxygenase; Albendazole monooxygenase (sulfoxide-forming); Albendazole sulfoxidase; aryl hydrocarbon hydroxylase; cholesterol 25-hydroxylase; CP33; CP34; CP35; CYP3A; CYP3A28; CYP3A3; CYP3A4; CYP3A5; CYPIIIA28; CYPIIIA3; CYPIIIA4; CYPIIIA5; cytochrome P450; cytochrome P450 3A28; cytochrome P450 3A3; Cytochrome P450 3A4; cytochrome P450 3A5; cytochrome P450 family 3 subfamily A member 4; cytochrome P450 family 3 subfamily A member 5; cytochrome P450 HLp; cytochrome P450 HLp2; cytochrome P450 NF-25; cytochrome P450, family 3, subfamily A, polypeptide 4; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; cytochrome P450, subfamily IIIA, polypeptide 4; cytochrome P450-PCN1; Cytochrome P450-PCN3; flavoprotein-linked monooxygenase; glucocorticoid-inducible P450; HLP; HLp2; microsomal monooxygenase; NF-25; Nifedipine oxidase; P450C3; P450-III, steroid inducible; P450PCN1; P450PCN3; P450-PCN3; PCN3; Quinine 3-monooxygenase; taurochenodeoxycholate 6-alpha-hydroxylase; Unknown (protein for MGC:127840); xenobiotic monooxygenase
Gene Symbols CYP3A4, CYP3A5
Host Species Mouse
Immunogen Synthetic peptide corresponding to residues E S R D G T V S G A, conjugated to ovalbumin.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1576, 1577, 282214, 507988, 526682
Target Species Bovine, Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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