Invitrogen™ CYP2C19 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA513669

Product Code. 10362520

Description

CYP2C19 Polyclonal Antibody for Western Blot, IHC (P)

CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.

Specifications

• Antigen: CYP2C19
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP2C19
• Gene Alias: (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CPCJ; CYP2C; CYP2C19; CYPIIC17; CYPIIC19; cyto; cytochrome P450 2C19; cytochrome P450 family 2 subfamily C member 19; cytochrome P-450 II C; cytochrome P450, family 2, subfamily C, polypeptide 19; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19; cytochrome P450-11A; Cytochrome P450-254C; Fenbendazole monooxygenase (4'-hydroxylating); flavoprotein-linked monooxygenase; mephenytoin 4'-hydroxylase; mephenytoin 4-hydroxylase; microsomal monooxygenase; P450-11A; P450-254C; P450C2C; P450IIC19; S-mephenytoin 4-hydroxylase; xenobiotic monooxygenase
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 1557
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P33261
• Gene Symbols: CYP2C19
• Immunogen: KLH conjugated synthetic peptide between 257-285 amino acids from the central region of human CYP2C19.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG