Invitrogen™ CYFIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA545585

Product Code. 15566872

Description

Peptide sequence: WAGCMIIVLL GQQRRFAVLD FCYHLLKVQK HDGKDEIIKN VPLKKMVERI Sequence homology: Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA. Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.

Specifications

• Antigen: CYFIP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cyfip1
• Gene Alias: CY; CYFIP; cyfip1; cyfip1 protein; cytoplasmic FMR1 interacting protein 1; cytoplasmic FMR1-interacting protein 1; Cytoplasmic FMR1-interacting protein 1 homolog; cytoplasmic FMRP interacting protein 1; E030028J09Rik; fb15a06; FLJ45151; FMR1-interacting protein 1; KIAA0068; l(7)1Rl; l71Rl; l7Rl1; LOW QUALITY PROTEIN: cytoplasmic FMR1-interacting protein 1; mKIAA0068; P140sra1; p140sra-1; pl-1; selective hybridizing clone; Shyc; Specifically Rac1-associated protein 1; Sra1; Sra-1; Unknown (protein for IMAGE:7152255); wu:fb15a06
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23191
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q7L576
• Gene Symbols: Cyfip1
• Immunogen: Synthetic peptide directed towards the C-terminal of human CYFIP1 (aa 1159-1208).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG