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Cyclosporin A, MedChemExpress

Product Code. 16471426
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Product Code. 16471426 Supplier Medchem Express Supplier No. HYB0579

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Description

MedChemExpress Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 adhesion.

Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 adhesion.

Specifications

Chemical Name or Material Cyclosporin A
Physical Form Solid
CAS 59865-13-3
Color White
Quantity 200 mg
Purity Grade Notes Research
Molecular Formula C62H111N11O12
For Use With (Application) COVID-19-immunoregulation
Synonym Cyclosporine A Ciclosporin A CsA
Solubility Information DMSO : 62.5 mg/mL (51.97 mM; Need ultrasonic) ∣Ethanol : 50 mg/mL (41.58 mM; Need ultrasonic)
SMILES C/C=C/C[C@H]([C@@H](O)[C@@]1(N(C)C([C@]([H])(C(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@]([H])(CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@@H](N(C([C@@]([H])(NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)=O)=O)=O)=O)=O)[H])C
Molecular Weight (g/mol) 1202.61
Formula Weight 1202.61
Percent Purity 98.0%
Grade Research
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