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Tocris Bioscience™ Cyclopamine

Description
Inhibitor of hedgehog (Hh) signaling, likely via direct inhibition of Smoothened, the accessory protein to the putative Hh receptor Patched. Anticancer and teratogenic in vivo. Depletes stem-like cancer cells in glioblastoma and blocks tumor engraftment. Can also be used to induce differentiation of human embryonic stem cells (hESCs) into hormone-expressing endocrine cells.
Specifications
Specifications
| CAS | 4449-51-8 |
| Quantity | 1 mg |
| Molecular Formula | C27H41NO2 |
| Formula Weight | 411.63 |
| Purity | >97% |
| Molecular Weight (g/mol) | 411.63 |
| Chemical Name or Material | Cyclopamine |
Product Title
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