Invitrogen™ Cyclin T2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5100709

Product Code. 16627194

Description

Antibody detects endogenous levels of total CCNT2.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: Cyclin T2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCNT2
• Gene Alias: 2900041I18Rik; C81304; Ccnt2; cyclin T2; cyclin T2a; cyclin T2b; cyclin-T2; CycT2; CycT2a; CycT2b; SDS-stable vimentin-bound DNA fragment HEF42VIM22; subunit of positive elongation transcription factor b
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 304758, 72949, 905
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O60583, Q7TQK0
• Gene Symbols: CCNT2
• Immunogen: A synthesized peptide derived from human CCNT2(Accession O60583), corresponding to amino acid residues S542-D592.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG