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Invitrogen™ Cyclin C Polyclonal Antibody
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Product Code. 16508361
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Quantity:
100 μL
Unit Size:
100µL
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16508361 100 μL 100µL
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Product Code. 16508361 Supplier Invitrogen™ Supplier No. PA593046

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAGNFWQSSH YLQWILDKQD LLKERQKDLK FLSEEEYWKL QIFFTNVIQA LGEHLKLRQQ VIATATVYFK RFYARYSLKS IDPVLMAPTC VFLASKVEEF GVVSNTRLIA AATSVLKTRF SYAFPKEFPY RMNHILECEF YLLELMDCCL IVYHPYRPLL QYVQDMGQED MLLPLAWRIV NDTYRTDLCL LYPPFMIALA CLHVACVVQQ KDARQWFAEL SVDMEKILEI IRVILKLYEQ WKNFDERKEM ATILSKMPKP KPPPNSEGEQ GPNGSQNSSY SQS; Positive Samples: MCF7, NIH/3T3, Mouse liver, Mouse kidney, Rat liver; Cellular Location: Nucleus.

Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock out of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk 8, a novel protein kinase of the cdk family. It is suggested that cyclin C and cdk 8 control RNA polymerase II function. Human cdk 8 cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin C
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.95 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CCNC
Gene Accession No. P24863, P39947, Q62447
Gene Alias AI451004; AU020987; CCNC; CG1C; CycC; cyclin C; cyclin-C; dJ199J3.4 (cyclin C); hSRB11; SRB11 homolog
Gene Symbols CCNC
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human Cyclin C (NP_0051812).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114839, 51813, 892
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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