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  5. Tocris Bioscience™ CY 09

Tocris Bioscience™ CY 09

Product Code. 18791108
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50 mg
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18791108 50 mg 50mg
18783198 10 mg 10mg
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Product Code. 18791108 Supplier Tocris Bioscience™ Supplier No. 6436/50

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Description

Inflammasomes Inhibitors

CY 09 is a NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation. Displays therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes. Exhibits no activity for hERG (10 μM).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid
CAS 1073612-91-5
Quantity 50 mg
Molecular Formula C19H12F3NO3S2
Purity 98%
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