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PeproTech CXCL12 alpha (SDF-1 alpha) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
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Product Code. 17873933
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2 x 500 μg
25 μg
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500 μg
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1mg
25µg
500µg
50µg
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17873933 25 μg 25µg
17883853 50 μg 50µg
17834783 2 x 500 μg 1mg
30054778 500 μg 500µg
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Product Code. 17873933 Supplier PeproTech Supplier No. 500P164GBT25UG

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Description

Goat Polyclonal Antibody

AA Sequence of recombinant protein: KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK. Preparation: Produced from sera of goats immunized with highly pure recombinant Murine SDF-1alpha (CXCL12). Anti-Murine SDF-1alpha (CXCL12)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Murine SDF-1alpha by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine SDF-1alpha (500-P164G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine SDF-1alpha. Western Blot: To detect Murine SDF-1alpha by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Murine SDF-1alpha is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P164GBT-1MG will be provided as 2 x 500 μg

CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
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Specifications

Antigen CXCL12 alpha (SDF-1 alpha)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.1-1.0 mg/mL
Conjugate Biotin
Formulation PBS with no preservative
Gene CXCL12
Gene Accession No. P40224
Gene Alias 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; H-SDF-1-alpha; Intercrine reduced in hepatomas; IRH; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; SDF 1 a; SDF 1 alpha; SDF 1α; SDF1; SDF-1; SDF1 alpha; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); SDF1α; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1
Gene Symbols CXCL12
Host Species Goat
Immunogen E.coli-derived, 7.9 kDa Recombinant Murine SDF-1alpha (CXCL12).
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20315
Target Species Mouse
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
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