Invitrogen™ CXCL11 Monoclonal Antibody (10C6)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA1032

Product Code. 12897752

Description

MA1032 has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody MA1033B (biotinylated conjugate of clone 22F1). Typical dilutions for sandwich ELISA include 1 μg/mL for coating and 0.125-0.25 μg/mL for detection. The Molecular weight is ~8303 Da from positions 22 - 94 as determined by MALDI.

Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.

Specifications

• Antigen: CXCL11
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O14625
• Gene Symbols: CXCL11
• Immunogen: Full length recombinant protein expressed in E-Coli.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 10C6
• Conjugate: Unconjugated
• Gene: CXCL11
• Gene Alias: betaR1; beta-R1; b-R1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 11; CXC; CXC motif chemokine; C-X-C motif chemokine 11; C-X-C motif chemokine ligand 11; Cxc11; CXCL; CXCL11; H174; Interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; IP9; IP-9; Itac; I-TAC; MGC102770; Scyb11; Scyb9b; small inducible cytokine B11; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; small-inducible cytokine B11
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 6373
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid