Invitrogen™ CXCL1/CXCL2/CXCL3 Monoclonal Antibody (29702)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA523920

Product Code. 15533612

Description

In direct ELISAs, 100% cross-reactivity with recombinant mouse (rm) CXCL2 is observed and no cross-reactivity with recombinant human (rh) VIC, rmVIC, rhCCL3L1, rhCCL4L1, or recombinant canine IL-8 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.

Specifications

• Antigen: CXCL1/CXCL2/CXCL3
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P09341, P19875, P19876
• Gene Symbols: CXCL1, CXCL2, CXCL3
• Immunogen: E. coli-derived recombinant human CXCL3 Ala35-Asn107.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: 29702
• Conjugate: Unconjugated
• Gene: CXCL1
• Gene Alias: C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); chemokine (C-X-C motif) ligand 2; chemokine (C-X-C motif) ligand 3; CINC-2a; CINC-2b; CXC; CXC motif chemokine; C-X-C motif chemokine 1; C-X-C motif chemokine 2; C-X-C motif chemokine 3; C-X-C motif chemokine ligand 1; C-X-C motif chemokine ligand 2; C-X-C motif chemokine ligand 3; CXCL; CXCL1; CXCL2; CXCL3; fibroblast secretory protein; FSP; GRO; GRO a; gro beta; gro gamma; GRO α; GRO1; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); GRO2; GRO2 oncogene; GRO3; GRO3 oncogene; GROa; GROalpha; GRO-alpha(1-73); GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73); GROB; Gro-beta; GRO-beta(5-73); GRO-beta-T; GROG; GRO-gamma; GRO-gamma(1-73); GRO-gamma(5-73); Growth-regulated alpha protein; growth-regulated protein beta; Growth-regulated protein gamma; GROα; Hematopoietic synergistic factor; HSF; Macrophage inflammatory protein 2-alpha; macrophage inflammatory protein 2-beta; melanoma growth stimulating activity, alpha; Melanoma growth stimulatory activity; melanoma growth stimulatory activity alpha; melanoma growth stimulatory activity beta; melanoma growth stimulatory activity gamma; MGSA; MGSA alpha; MGSA beta; MGSA gamma; MGSA-a; MGSA-b; MIP2; MIP2A; MIP-2a; MIP2-alpha; MIP2B; MIP-2b; MIP2-beta; NAP3; NAP-3; Neutrophil-activating protein 3; SB-251353; SCYB1; SCYB2; SCYB3
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 2919, 2920, 2921
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized