CX3CR1 Monoclonal Antibody (2A9-1), APC, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-6099-41

Product Code. 15528176

Description

Description: This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family. CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g. CD8+, CD4+, and gamma/delta), and monocytes. In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia. Little to no CX3CR1 surface expression can be detected on B cells and granulocytes. Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes. The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B. Applications Reported: This 2A9-1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 2A9-1 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

CX3CR1 Monoclonal antibody specifically detects CX3CR1 in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: CX3CR1
• Classification: Monoclonal
• Concentration: 5 μL/Test
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
• Gene Accession No.: P49238
• Gene Symbols: CX3CR1
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1524
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: 2A9-1
• Conjugate: APC
• Gene: CX3CR1
• Gene Alias: Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28
• Host Species: Rat
• Quantity: 25 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

For Research Use Only.