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Invitrogen™ CUEDC1 Polyclonal Antibody

Product Code. 12858492
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Quantity:
100 μg
Unit Size:
100µg
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12858492 100 μg 100µg
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Product Code. 12858492 Supplier Invitrogen™ Supplier No. PA520619

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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat liver tissue lysate. PA5-20619 can be used with blocking peptide PEP-0739.

The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CUEDC1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CUEDC1
Gene Accession No. Q8R3V6, Q9NWM3
Gene Alias AI841487; C330016O16Rik; CUE domain containing 1; CUE domain-containing protein 1; Cuedc1; RGD1304861
Gene Symbols CUEDC1
Host Species Rabbit
Immunogen A 16 amino acid peptide near the carboxy terminus of human CUEDC1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103841, 303419, 404093
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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