Invitrogen™ CTU2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA559441

Product Code. 15707301

Description

Immunogen sequence: LSPDSFCLGF SEGAACGQSL EERSKTLAEV KPILQATGFP WHVVALEEVF SLPPSVLWCS AQELVGSEGA YKAAVDSFLQ QQH Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 70%.

Cytoplasmic tRNA 2-thiolation protein 2 (CUT2), also named as C16orf84 or NCS2, is a 515 amino acid protein, which belongs to the CUT2 family. C16orf84 localizes in the cytoplasm and Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). C16orf84 may act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thio-carboxylated URM1 onto the uridine of tRNAs at wobble position.

Specifications

• Antigen: CTU2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CTU2
• Gene Alias: 2310061F22Rik; C16orf84; Ctu2; Cytoplasmic tRNA 2-thiolation protein 2; cytoplasmic tRNA 2-thiolation protein 2 {ECO:0000255; cytosolic thiouridylase subunit 2; cytosolic thiouridylase subunit 2 homolog; cytosolic thiouridylase subunit 2 homolog (S. pombe); HAMAP-Rule:MF_03054}; Ncs2; UPF0432
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 348180
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q2VPK5
• Gene Symbols: CTU2
• Immunogen: Recombinant protein corresponding to Human CTU2. Recombinant protein control fragment (Product #RP-98583).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG