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Gibco™ CTS™ OpTmizer™ One SFM
Description
Gibco CTS OpTmizer One SFM is a novel animal-origin-free (AOF) serum-free medium (SFM) formulation developed for the growth and expansion of human T lymphocytes used in cell therapies. This medium improves cell count and early memory phenotype throughout all stages of expansion.
Benefits:
- Provides enhanced T-cell expansion and expression of early memory phenotype makers compared to other chemically defined media
- Demonstrates flexibility across culture vessels. In both G-Rex™ plates and rocking bioreactors, it supports scale-up while maintaining desired T-cell phenotype.
- Expands both healthy and disease state donors
- Supports efficient viral and non-viral editing with downstream expansion
- Mitigates risk of contaminants and variability associated with animal-sourced materials
- Supports scale-up via larger catalog pack sizes
Features:
- Animal-origin-free (AOF) formulation
- Serum-free—designed without the need for serum or serum replacement
- No separate components—no need to mix basal medium with supplement to obtain complete medium
- Yields high density cultures
- Supports T-cell activation using CTS Dynabeads (both passive release CD3/CD28 (Cat. No.40203D) and detachable CD3/CD28 (Cat No. A56992))
- Available in 1 L bottle, 1 L bag, 5 L bag, and 10 L bag options
Increased efficiency and consistent performance:
CTS OpTmizer One SFM is an AOF formulation that supports high density cultures in static and dynamic vessels. It displays consistent performance for T-cell expansion, with better early memory phenotype at early stages.
Simplify your transition into clinical research:
The Gibco Cell Therapy Systems (CTS) portfolio offers a broad array of products for use in cell therapy applications, including media, reagents, growth factors, enzymes, cell selection/expansion reagents, and devices. CTS products deliver:
- Reduced burden in qualifying reagents
- Appropriate certificates of analysis and origin available
- Convenient access to our Drug Master File (DMF)
Specifications
Specifications
| Classification | Animal Origin-free, Serum-free, cGMP |
| Form | Liquid |
| Serum Level | Serum-free |
| Sterility | Sterile-filtered |
| Sterilization Method | 0.2 μm Sterile-filtered |
| With Additives | None |
| Without Additives | No Glutamine, No Phenol Red |
| Product Line | CTS OpTmizer |
| Quantity | 1 L |
| Format | Bottle |
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Frequently Asked Questions (FAQs)
The Gibco Cell Therapy Systems (CTS) portfolio of cell and gene therapy products are GMP manufactured, safety tested, and backed by regulatory documentation to support your transition from discovery through clinical and commercial manufacturing. Through our CTS solutions, we are committed to helping customers streamline therapeutic development, minimize risk, and ease the burden on their quality systems. Learn more here.
Yes. CTS OpTmizer One SFM offers excellent performance in a range of culture vessels, from static to dynamic bioreactors.
No. CTS OpTmizer One SFM was designed to be used without serum or serum replacement supplementation.
Yes, all protein within CTS OpTmizer One SFM is recombinant.
No. The most consistent and reproducible results are seen when L-glutamine is added to CTS OpTmizer One SFM at the point of use.
For Research Use or Manufacturing of Cell, Gene, or Tissue-Based Products. CAUTION: Not intended for direct administration into humans or animals.
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