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Invitrogen™ CTRP3 Polyclonal Antibody
Description
A suggested positive control is mouse heart tissue lysate. PA5-20149 can be used with blocking peptide PEP-0269.
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development.
Specifications
Specifications
| Antigen | CTRP3 |
| Applications | Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | C1qtnf3 |
| Gene Accession No. | Q9BXJ4, Q9ES30 |
| Gene Alias | 2310005P21Rik; C1ATNF3; C1q and tumor necrosis factor related protein 3; C1qtnf3; cartducin; cartonectin; collagenous repeat-containing sequence 26 kDa protein; collagenous repeat-containing sequence of 26-kDa; complement C1q tumor necrosis factor-related protein 3; Corcs; CORS; CORS26; CORS-26; CTRP3; Secretory protein CORS26; UNQ753/PRO1484 |
| Gene Symbols | C1qtnf3 |
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