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Invitrogen™ CTRP1 Polyclonal Antibody

Product Code. 12808312
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Quantity:
100 μg
Unit Size:
100µg
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12808312 100 μg 100µg
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Product Code. 12808312 Supplier Invitrogen™ Supplier No. PA520146

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human kidney tissue lysate. PA5-20146 can be used with blocking peptide PEP-0266.

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CTRP1
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene C1QTNF1
Gene Accession No. Q5XIG2, Q9BXJ1, Q9QXP7
Gene Alias 1600017K21Rik; C1q and tumor necrosis factor related protein 1; C1qtnf1; Complement C1q tumor necrosis factor-related protein 1; Ctrp1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein; GIP; putative secreted protein ZSIG37; UNQ310/PRO353; Zsig37
Gene Symbols C1QTNF1
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the amino-terminus of human CTRP1.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114897, 303701, 56745
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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