Invitrogen™ CTRP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520145

Product Code. 12898302

Description

A suggested positive control is MDA-MB-361 cell lysate. PA5-20145 can be used with blocking peptide PEP-0265.

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.

Specifications

• Antigen: CTRP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C1QTNF1
• Gene Alias: 1600017K21Rik; C1q and tumor necrosis factor related protein 1; C1qtnf1; Complement C1q tumor necrosis factor-related protein 1; Ctrp1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein; GIP; putative secreted protein ZSIG37; UNQ310/PRO353; Zsig37
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114897, 56745
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9BXJ1, Q9QXP7
• Gene Symbols: C1QTNF1
• Immunogen: A 16 amino acid peptide from near the center of human CTRP1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG